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Topical NSAIDs may not be helpful for people with inflammatory conditions, such as rheumatoid arthritis, because their pain is more widespread. They are often recommended for treating isolated areas of pain and inflammation caused by osteoarthritis, particularly in the hands and knees.

have a condition affecting your connective tissue, such as lupusĭepending on what’s causing your pain, your doctor may first recommend trying a topical NSAID, such as ibuprofen, ketoprofen, felbinac and piroxicam, as they may cause fewer side effects than tablets.

problems with your blood pressure, circulation, or bleeding.

have problems with your stomach, intestines, or bowels such as ulcerative colitis or Crohn’s disease.

might be pregnant or you’re breastfeeding.

The type of NSAID you are prescribed may depend upon other health issues, such as if you: Your doctor should discuss with you the type of NSAID that’s best for you, and they should arrange regular check-ups to review your progress.

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a cream, gel, spray, plaster, or mousse you apply to the skin – known as topical NSAIDs.

a suppository, a medicine you place in your bottom.

There are around 20 NSAIDs that are commonly prescribed, these include: You are likely to be prescribed a short course of an NSAID at the lowest possible dose to treat your pain. These drugs can cause side effects, particularly if you take them for a long period of time. If you’ve been using over-the-counter NSAIDs, such as ibuprofen or aspirin, your doctor may recommend you continue taking them under their guidance, before considering another treatment.

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You should feel some relief within an hour of using NSAIDs, but it can take several days or weeks before you feel the full benefit. NSAIDs, or non-steroidal anti-inflammatory drugs, are recommended for short-term relief from pain, fever, and swelling or stiffness around your bones and joints.

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If paracetamol isn’t helping, a healthcare professional may recommend other treatments, such as a programme of exercise, physiotherapy, or a stronger type of pain relief. Taking too much paracetamol can cause liver failure. However, be careful if you’re taking medicines for migraines, coughs, colds and flu, or compound painkillers, because these drugs often already contain paracetamol.

You can take paracetamol with NSAIDs, such as ibuprofen or aspirin, or with another painkiller called codeine. If you have problems such as lower back pain, or osteoarthritis, taking paracetamol alone may not be the most effective treatment. Though paracetamol is safe for most people, your doctor may advise against using it if you have another health issue. It should start working within the hour and last for around five hours. You can take paracetamol as a tablet, capsule, liquid, or as tablets that dissolve in water. Paracetamol is used to reduce fever and can help manage mild to moderate aches and pain. If over-the-counter drugs haven’t improved your pain your doctor may prescribe stronger pain medication or another type of treatment. Taking other over-the-counter drugs for longer than ten days without guidance from a healthcare professional, could increase your risk of side effects such as problems with your stomach, heart, liver, or kidneys. Painkillers containing codeine should only be taken for three days at most without medical advice.

have a condition affecting your connective tissue, such as lupus.

drink more than 14 units of alcohol a week.

have had problems with your heart, liver, kidneys, blood pressure, or circulation.

have had ulcers or bleeding in your stomach.

have problems with your liver or kidneys.

Seek advice from a pharmacist or healthcare professional before taking them if you: However, some people may need to be cautious.

Most people can use over-the-counter pain relief. Your healthcare professional may also recommend using these drugs under their guidance over the long term, to help manage your condition.

compound painkillers – co-codamol, paracetamol and ibuprofen, ibuprofen and codeine.

NSAIDs – ibuprofen, aspirin, and diclofenac gel.

They are often recommended for managing mild to moderate pain yourself, over a short period of time. Some painkillers and NSAIDs are available to buy from pharmacies, shops, or supermarkets.